Susceptibility to Aneuploidy in Young Mothers of Down Syndrome Children

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Susceptibility to Aneuploidy in Young Mothers of Down Syndrome Children

We recently observed an increased frequency of binucleated micronucleated lymphocytes in women who had a Down syndrome (DS) child before 35 years of age and the fluorescence in situ hybridization analysis revealed that micronuclei were mainly originating from chromosomal malsegregation events, including chromosome 21 malsegregation. That study indicated that women who have a DS child at a young...

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Stress trajectories in mothers of young children with Down syndrome.

BACKGROUND In this study, we investigated the early development of stress in mothers of children with Down syndrome, compared with mothers of children with developmental disabilities of mixed aetiologies. Growth modelling analyses were used to explore: (1) whether mothers of children with Down syndrome demonstrated distinct patterns of stress during their children's early development, compared ...

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The effect of reality therapy on self-efficacy in mothers of children with Down syndrome

Introduction :Down syndrome is the most prevalent abnormal chromosomal disorder in human and the best known genetic cause of mental retardation which lays the foundations for physical and congenital defects and abnormalities. Abnormal behaviors of children with Down syndrome impair their mother's self-efficacy. The present study was conducted to investigate the effect of reality therapy on gene...

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ژورنال

عنوان ژورنال: The Scientific World JOURNAL

سال: 2009

ISSN: 1537-744X

DOI: 10.1100/tsw.2009.122